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Context Info
Confidence 0.43
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.67
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (S100a6) nuclear envelope (S100a6) plasma membrane (S100a6)
nucleus (S100a6) cytoplasm (S100a6)
Anatomy Link Frequency
stroma 1
brain 1
S100a6 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 1 88.08 High High
cytokine 16 87.12 High High
endometriosis 1 75.92 Quite High
Inflammation 80 75.28 Quite High
psoriasis 1 21.52 Low Low
Abeta 12 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Corneal Neovascularization 6 97.44 Very High Very High Very High
Anaplastic Astrocytoma 1 89.72 High High
Brain Injury 1 89.20 High High
Cv Unclassified Under Development 1 88.08 High High
Infarction 1 87.36 High High
Stress 13 86.00 High High
Disease 13 85.44 High High
Syndrome 1 83.84 Quite High
Death 7 78.24 Quite High
Endometriosis (extended) 1 75.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Microarray profiling revealed that S100A4, S100A6, S100A8, S100A9, and S100A13 were upregulated in both CorNV models, with S100A8 and S100A9 manifesting the most significant changes compared to the normal animals.
Positive_regulation (upregulated) of S100A6
1) Confidence 0.43 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2994359 Disease Relevance 0.65 Pain Relevance 0.21
S100B, along with S100A1 and S100A6, are the most abundant S100 proteins in the brain of several species including mice and rats.
Positive_regulation (abundant) of S100A6 in brain
2) Confidence 0.22 Published 2009 Journal J Transl Med Section Body Doc Link PMC2666642 Disease Relevance 0.88 Pain Relevance 0.08
Therefore, PRA seems also to be strongly induced in the uterine stroma during early pregnancy.
Positive_regulation (induced) of PRA in stroma
3) Confidence 0.03 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1586009 Disease Relevance 0.15 Pain Relevance 0

General Comments

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