INT197603

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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.67
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Dlat) transferase activity, transferring acyl groups (Dlat)
Dlat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 54 95.40 Very High Very High Very High
agonist 25 80.08 Quite High
Hippocampus 9 61.92 Quite High
withdrawal 8 57.36 Quite High
Pyramidal cell 22 38.88 Quite Low
Glutamate 1 38.48 Quite Low
antagonist 1 12.96 Low Low
imagery 7 5.00 Very Low Very Low Very Low
Neuronal excitability 5 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 52 95.40 Very High Very High Very High
Death 8 75.84 Quite High
Targeted Disruption 9 63.72 Quite High
Apoptosis 11 51.68 Quite High
Prolactinoma 1 50.00 Quite Low
Pituitary Cancer 8 30.16 Quite Low
Cv General 4 Under Development 1 26.76 Quite Low
Stress 1 24.16 Low Low
Cognitive Disorder 1 14.88 Low Low
Cancer 37 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we evaluated the potential neuroprotective action of the natural estrogen E2 and two synthetic estrogenic compounds that do not bind ER-?
Positive_regulation (evaluated) of E2 Neg (not) Binding (bind) of
1) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2799530 Disease Relevance 0.62 Pain Relevance 0.35
The actions of E2 and P are primarily mediated via binding to specific intracellular receptors in the target cells.
Positive_regulation (mediated) of E2 Binding (binding) of
2) Confidence 0.09 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1586009 Disease Relevance 0 Pain Relevance 0
The expression of VEGF mRNA was also markedly elevated with treatment with E2.
Positive_regulation (elevated) of E2 Binding (treatment) of
3) Confidence 0.06 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875861 Disease Relevance 0.05 Pain Relevance 0

General Comments

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