INT197674

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.63
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Arg1) aging (Arg1) cytoplasm (Arg1)
Arg1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 9 99.72 Very High Very High Very High
Inflammation 13 97.80 Very High Very High Very High
Central nervous system 5 5.00 Very Low Very Low Very Low
Thalamus 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 97.80 Very High Very High Very High
Infection 29 94.84 High High
Frailty 3 34.40 Quite Low
Disease 12 17.72 Low Low
Weight Gain 3 6.36 Low Low
African Trypanosomiasis 13 5.84 Low Low
Breast Cancer 11 5.00 Very Low Very Low Very Low
Body Weight 9 5.00 Very Low Very Low Very Low
Endometriosis (extended) 5 5.00 Very Low Very Low Very Low
Reprotox - General 2 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, increased ER expression and decreased arginase activity were observed in both tamoxifen-infused and ovariectomized rats in this study.
Positive_regulation (increased) of Gene_expression (expression) of arginase
1) Confidence 0.33 Published 2006 Journal BMC Womens Health Section Body Doc Link PMC1590006 Disease Relevance 0 Pain Relevance 0
Anti-inflammatory interleukins such as IL-4 and IL-10 are inducers of arginase isoforms, although these cytokines are known to act on the expression of arginase I, but not that of arginase II [28].
Positive_regulation (act) of Gene_expression (expression) of arginase associated with inflammation and cytokine
2) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2821905 Disease Relevance 0.63 Pain Relevance 0.44

General Comments

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