INT197681

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Context Info
Confidence 0.48
First Reported 2005
Last Reported 2010
Negated 5
Speculated 4
Reported most in Body
Documents 40
Total Number 44
Disease Relevance 33.72
Pain Relevance 2.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CHDH)
Anatomy Link Frequency
leaflets 2
body 2
cardiac muscle cell 1
CHDH (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 214 98.64 Very High Very High Very High
Pain 42 97.20 Very High Very High Very High
imagery 29 75.60 Quite High
Osteoarthritis 2 68.80 Quite High
potassium channel 2 40.64 Quite Low
Calcium channel 3 39.24 Quite Low
beta blocker 21 32.32 Quite Low
aspirin 21 30.04 Quite Low
ischemia 37 5.00 Very Low Very Low Very Low
Inflammation 19 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 1606 100.00 Very High Very High Very High
Cv Unclassified Under Development 1531 100.00 Very High Very High Very High
Coronary Heart Disease 88 100.00 Very High Very High Very High
Canine Hip Dysplasia 58 100.00 Very High Very High Very High
Stroke 274 99.92 Very High Very High Very High
Diabetes Mellitus 69 99.84 Very High Very High Very High
Body Weight 30 99.80 Very High Very High Very High
Intrauterine Growth Retardation 1 99.76 Very High Very High Very High
Disorder Of Lipid Metabolism 287 99.64 Very High Very High Very High
Obesity 167 99.42 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data suggest that the early recognition of CHD may also lead to greater attention to risk factor identification and treatment.
CHD Binding (recognition) of associated with coronary artery disease
1) Confidence 0.48 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 1.50 Pain Relevance 0.55
Almost half of the women and 70% of the men did not have CHD recognized prior to incident AMI.
CHD Binding (recognized) of associated with coronary artery disease
2) Confidence 0.42 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 1.40 Pain Relevance 0.51
There were also within gender differences with older people more likely to have CHD recognized and diagnosed prior to incident AMI.
CHD Spec (likely) Binding (recognized) of associated with coronary artery disease
3) Confidence 0.42 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 1.19 Pain Relevance 0.05
It is possible that men have fewer visits for CHD like symptoms due either to the lack of such symptoms or the failure to recognize or desire to have such symptoms evaluated.
CHD Binding (recognize) of associated with coronary artery disease
4) Confidence 0.32 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 0.89 Pain Relevance 0.14
The pre-incident AMI period may provide a significant opportunity for primary care physicians to recognize and treat CHD risk factors, potentially preventing or delaying cardiac events and death.[16-18,23-28]
CHD Binding (recognize) of associated with coronary artery disease and death
5) Confidence 0.31 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 0.84 Pain Relevance 0
Earlier recognition of CHD may be associated with higher levels of recognition and treatment of CHD risk factors that may delay incident AMI.
CHD Binding (recognition) of
6) Confidence 0.31 Published 2007 Journal BMC Fam Pract Section Abstract Doc Link PMC1853095 Disease Relevance 0.10 Pain Relevance 0
In conclusion, these data suggest that there is a gender and age differential in the recognition of CHD prior to incident AMI.
CHD Binding (recognition) of associated with coronary artery disease
7) Confidence 0.31 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 0.72 Pain Relevance 0
The diagnosis of CHD increases the likelihood of recognizing and treating CHD risk factors suggesting that earlier CHD diagnosis may provide greater opportunities to address undiagnosed and minimally treated potentially modifiable CHD risk factors before the first cardiac event thereby preventing or delaying CHD events.


CHD Binding (recognizing) of associated with coronary artery disease
8) Confidence 0.31 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC1853095 Disease Relevance 0.80 Pain Relevance 0
The leaflets tended to score lowest on the section related to information about CHD but highest on the section about treatment choices.
CHD Binding (information) of in leaflets associated with coronary artery disease
9) Confidence 0.30 Published 2006 Journal BMC Health Serv Res Section Body Doc Link PMC1590021 Disease Relevance 0.33 Pain Relevance 0
Each information leaflet also included general information about CHD, suggestions for reducing the risk factor and space for documenting phone numbers and appointment details.
CHD Binding (information) of in leaflet associated with coronary artery disease
10) Confidence 0.30 Published 2006 Journal BMC Health Serv Res Section Body Doc Link PMC1590021 Disease Relevance 0.31 Pain Relevance 0
Changes in HDL-C and LDL-C were associated with CHD incidence in the treatment group while changes in TG were not.
CHD Binding (associated) of associated with coronary artery disease and disorder of lipid metabolism
11) Confidence 0.21 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835557 Disease Relevance 1.53 Pain Relevance 0
However, the multiple regression analyses indicated that the interactions between CHD and body weight contributed significantly to explain the improvement in pain signs.
CHD Binding (interactions) of in body associated with pain, body weight and canine hip dysplasia
12) Confidence 0.20 Published 2005 Journal Acta Vet Scand Section Body Doc Link PMC2202790 Disease Relevance 0.93 Pain Relevance 0.36
The interactions between CHD and body weight apparently contributed to explain the improvement in pain signs in this study.
CHD Binding (interactions) of in body associated with pain, body weight and canine hip dysplasia
13) Confidence 0.15 Published 2005 Journal Acta Vet Scand Section Body Doc Link PMC2202790 Disease Relevance 1.54 Pain Relevance 0.29
The association of complex CHD with intrauterine growth retardation has been well established in numerous reports over the past six decades [17–26].
CHD Binding (association) of associated with intrauterine growth retardation and coronary heart disease
14) Confidence 0.15 Published 2010 Journal International Journal of Pediatrics Section Body Doc Link PMC2938447 Disease Relevance 1.13 Pain Relevance 0.22
However, the association between CRP genotype and CHD has not been confirmed by other studies or meta-analyses [19], [25], [27].
CHD Binding (association) of associated with coronary artery disease
15) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2507732 Disease Relevance 1.03 Pain Relevance 0
In addition to its importance in understanding the causal role of CRP with CHD, it has also been suggested that determining the association of variation in CRP with CHD may be beneficial in its own right.[20] In a recent review, Hage and Szalai noted the paucity and inconsistencies of studies examining SNPs in CRP with cardiovascular endpoints, but suggested that if it could be established that variants in CRP were robustly associated with CHD events then CRP gene profiling could have clinical utility in disease prediction.[20]
CHD Binding (association) of associated with cv unclassified under development and disease
16) Confidence 0.13 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2507759 Disease Relevance 1.09 Pain Relevance 0
This finding was replicated in a subcohort that included only individuals with no CHD or diabetes (for contemporaneous association at mean age 61 age- and sex-adjusted beta?
CHD Neg (no) Binding (individuals) of associated with coronary artery disease and diabetes mellitus
17) Confidence 0.12 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2507732 Disease Relevance 0.44 Pain Relevance 0
The findings were also replicated in a subcohort including only individuals with no CHD or diabetes (n?
CHD Neg (no) Binding (individuals) of associated with coronary artery disease and diabetes mellitus
18) Confidence 0.12 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2507732 Disease Relevance 0.39 Pain Relevance 0
This approach was used by Casas et al.[12] to assess the association between CRP level and CHD among 3155 European men (985 CHD cases).
CHD Binding (association) of associated with cv unclassified under development
19) Confidence 0.11 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2507759 Disease Relevance 1.02 Pain Relevance 0
All analyses were conducted only on those with complete data for genotype, CRP levels and CHD (see table 1 for numbers).
CHD Binding (genotype) of associated with cv unclassified under development
20) Confidence 0.11 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2507759 Disease Relevance 0.38 Pain Relevance 0

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