INT197722

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.20
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (TFRC) peptidase activity (TFRC) mitochondrion (TFRC)
aging (TFRC) extracellular region (TFRC) cytoplasmic membrane-bounded vesicle (TFRC)
TFRC (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 97.28 Very High Very High Very High
Somatosensory cortex 55 91.04 High High
primary somatosensory cortex 34 89.52 High High
Inflammation 30 73.36 Quite High
Arthritis 1 71.16 Quite High
rheumatoid arthritis 3 54.20 Quite High
agonist 2 50.00 Quite Low
Osteoarthritis 1 41.04 Quite Low
chemokine 2 32.40 Quite Low
Potency 1 31.64 Quite Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 95 99.48 Very High Very High Very High
Overactive Bladder 4 98.12 Very High Very High Very High
Pain 4 97.28 Very High Very High Very High
Reprotox - General 1 1 97.04 Very High Very High Very High
Hematological Disease 3 90.00 High High
INFLAMMATION 33 73.36 Quite High
Arthritis 2 71.16 Quite High
Disease 11 59.88 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 59.20 Quite High
Rheumatoid Arthritis 3 54.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By contrast, in the ADHD group the grand-averaged TFR showed a modest early ERS response characterized by clusters of source power oscillating at theta, alpha, and beta frequencies.
Regulation (response) of TFR associated with attention deficit hyperactivity disorder
1) Confidence 0.14 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2266931 Disease Relevance 0.38 Pain Relevance 0.45
The secondary endpoints were immunological – changes in CD4, CD8, CD25, CD69 and CD71.
Regulation (changes) of CD71
2) Confidence 0.10 Published 2006 Journal Retrovirology Section Body Doc Link PMC1590049 Disease Relevance 0.25 Pain Relevance 0.10
Some of these genes include the Sp1 transcription factor, SGPP2, EVI5 gene, involved in cell cycle regulation, the transferrin receptor (TFRC) or C19ORF6, also called membralin, which has been associated with ovarian carcinoma (Figure 3).


Regulation (regulation) of transferrin receptor associated with reprotox - general 1
3) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2941452 Disease Relevance 0.48 Pain Relevance 0.17
With regard to genes involved in iron metabolism, ferritin and iron storage proteins were upregulated in FePro-labeled BMSCs and transferrin receptor was not changed.


Neg (not) Regulation (changed) of transferrin receptor
4) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2898800 Disease Relevance 0.09 Pain Relevance 0

General Comments

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