INT197724

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.99
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Rdh5)
Rdh5 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 20 90.64 High High
Neuropeptide 1 37.04 Quite Low
noradrenaline 1 35.80 Quite Low
Bile 13 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
beta blocker 2 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 15 87.16 High High
Insulin Resistance 5 84.64 Quite High
Metabolic Syndrome 25 76.36 Quite High
Disorder Of Lipid Metabolism 36 69.52 Quite High
Overweight 1 64.92 Quite High
Dyslipidemia /

Combined Dyslipidemia

16 63.08 Quite High
Cardiovascular Disease 6 54.44 Quite High
Diabetes Mellitus 29 54.04 Quite High
Neuroepithelial Neoplasms 12 50.00 Quite Low
Coronary Artery Disease 22 32.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Briefly, PPAR alpha is activated by fibric acids (e.g. bezafibrate) and form heterodimers with the 9-cis retinoic acid receptor (RXR).
9-cis Binding (heterodimers) of
1) Confidence 0.36 Published 2006 Journal Cardiovasc Diabetol Section Body Doc Link PMC1592077 Disease Relevance 0.82 Pain Relevance 0.05
In addition, the E domain offers the main surface for dimerization with the 9-cis retinoic acid receptor (RXR) as well as for interaction with regulatory proteins called cofactors.
9-cis Binding (interaction) of
2) Confidence 0.36 Published 2010 Journal PPAR Research Section Body Doc Link PMC2841252 Disease Relevance 0.11 Pain Relevance 0

General Comments

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