INT197808

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.81
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (MEN1, NME1) cytosol (MEN1, NME1) nucleus (MEN1, NME1)
cell differentiation (NME1) mitochondrion (NME1) small molecule metabolic process (NME1)
MEN1 (Homo sapiens)
NME1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 14 45.04 Quite Low
Somatostatin 6 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 12 100.00 Very High Very High Very High
Genomic Instability 2 98.40 Very High Very High Very High
Multiple Endocrine Neoplasia Type 1 208 88.12 High High
Cancer 118 75.44 Quite High
Syndrome 50 61.76 Quite High
Carcinoid 26 57.20 Quite High
Malignant Neoplastic Disease 6 33.36 Quite Low
Neuroendocrine Cancer 2 32.56 Quite Low
Disease 12 22.40 Low Low
Gastrinoma 34 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The binding of menin to Nm23H1 may be relevant also to the control of genomic stability, as Nm23H1 is associated to the centrosome that is involved in the maintenance of chromosome integrity.
menin Binding (binding) of Nm23H1 associated with genomic instability
1) Confidence 0.00 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1594566 Disease Relevance 0.97 Pain Relevance 0
Finally, menin interacts with the metastasis suppressor Nm23H1 [56].
menin Binding (interacts) of Nm23H1 associated with metastasis
2) Confidence 0.00 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1594566 Disease Relevance 0.84 Pain Relevance 0

General Comments

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