INT197809

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (MEN1, VIM) cytosol (MEN1, VIM) protein binding, bridging (MEN1)
embryo development (MEN1) DNA binding (MEN1) protein complex (MEN1)
Anatomy Link Frequency
glial cell 1
MEN1 (Homo sapiens)
VIM (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 7 22.48 Low Low
Somatostatin 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Endocrine Neoplasia Type 1 104 99.16 Very High Very High Very High
Metastasis 6 89.20 High High
Genomic Instability 1 74.24 Quite High
Cancer 59 52.88 Quite High
Syndrome 25 39.20 Quite Low
Carcinoid 13 34.64 Quite Low
Malignant Neoplastic Disease 3 10.80 Low Low
Neuroendocrine Cancer 1 10.00 Low Low
Gastrinoma 17 5.00 Very Low Very Low Very Low
Hypercalcemia 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although menin has been identified primarily as a nuclear protein, recent studies have reported its interaction with the glial fibrillary acid protein (GFAP) and with vimentin (components of intermediate filaments (IFs)), suggesting a putative role in glial cell oncogenesis.
menin Binding (interaction) of vimentin in glial cell
1) Confidence 0.04 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1594566 Disease Relevance 0.52 Pain Relevance 0

General Comments

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