INT197836

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 3.16
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MEN1) nucleolus (MEN1) nucleus (MEN1)
protein binding, bridging (MEN1) embryo development (MEN1) DNA binding (MEN1)
Anatomy Link Frequency
parathyroid 2
MEN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 1 72.96 Quite High
depression 1 67.52 Quite High
imagery 7 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Endocrine Neoplasia Type 1 104 100.00 Very High Very High Very High
Hypercalcemia 15 100.00 Very High Very High Very High
Hyperplasia 2 96.80 Very High Very High Very High
Cancer 59 94.48 High High
Parathyroid Cancer 4 93.88 High High
Insulinoma 6 76.36 Quite High
Gastrinoma 17 75.76 Quite High
Carcinoid 13 69.60 Quite High
Depression 1 67.52 Quite High
Confusion 1 64.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PHPT in MEN1 manifests with hypercalcaemia as a result of overproduction of parathyroid hormone (PTH) by tumoural and supernumerary parathyroid glands.
Positive_regulation (overproduction) of Gene_expression (overproduction) of MEN1 in parathyroid associated with multiple endocrine neoplasia type 1 and hypercalcemia
1) Confidence 0.50 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1594566 Disease Relevance 3.16 Pain Relevance 0.07

General Comments

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