INT197842

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 5.89
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PHPT1) cytoplasm (PHPT1)
Anatomy Link Frequency
skeleton 1
parathyroid 1
PHPT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 2 86.32 High High
Central nervous system 2 84.08 Quite High
Somatostatin 6 6.48 Low Low
imagery 14 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Dopamine 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Endocrine Neoplasia Type 1 208 100.00 Very High Very High Very High
Hypercalcemia 30 100.00 Very High Very High Very High
Hyperplasia 4 97.12 Very High Very High Very High
Kidney Stones 4 96.36 Very High Very High Very High
Hypertension 2 95.84 Very High Very High Very High
Cancer 118 94.80 High High
Volume Depletion And Dehydration 2 94.24 High High
Parathyroid Cancer 8 94.20 High High
Overactive Bladder 2 91.96 High High
Polyuria 2 91.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PHPT in MEN1 manifests with hypercalcaemia as a result of overproduction of parathyroid hormone (PTH) by tumoural and supernumerary parathyroid glands.
Gene_expression (overproduction) of PHPT in parathyroid associated with multiple endocrine neoplasia type 1 and hypercalcemia
1) Confidence 0.06 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1594566 Disease Relevance 3.17 Pain Relevance 0.07
4) skeleton – increased bone resorption and increased fracture risk, mainly in women who manifest PHPT before 35 years of age;
Gene_expression (manifest) of PHPT in skeleton associated with hypercalcemia
2) Confidence 0.05 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1594566 Disease Relevance 2.72 Pain Relevance 0.09

General Comments

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