INT19787

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Context Info
Confidence 0.30
First Reported 1990
Last Reported 1999
Negated 1
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Tyr) cell proliferation (Tyr) oxidoreductase activity (Tyr)
cytoplasm (Tyr)
Tyr (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 8 100.00 Very High Very High Very High
melanocortin 1 receptor 2 75.00 Quite High
Eae 1 65.68 Quite High
opioid receptor 1 35.44 Quite Low
narcan 1 25.00 Low Low
Opioid 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Skin Cancer 5 85.04 High High
Cancer 2 78.40 Quite High
Metastasis 1 45.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of the enkephalin metabolites, Tyr, des-Tyr-[Leu]enkephalin (GGFL), and Tyr-Gly-Gly (YGG), on acquisition of an active avoidance task following their IP administration to mice were determined.
Spec (determined) Regulation (effects) of Tyr associated with enkephalin
1) Confidence 0.30 Published 1990 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 2093169 Disease Relevance 0 Pain Relevance 0.55
Although tyrosinase activity and the protein level for tyrosinase and TRP-2, but not for TRP-1, were increased in the high metastatic hybrids versus the other cells, no significant changes in mRNA either for tyrosinase or for TRPs were observed in them.
Neg (no) Regulation (changes) of tyrosinase
2) Confidence 0.19 Published 1999 Journal Pigment Cell Res. Section Abstract Doc Link 10614575 Disease Relevance 0.46 Pain Relevance 0.13

General Comments

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