INT197971

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 2.43
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prdx5) oxidoreductase activity (Prdx5) peroxisome (Prdx5)
cytoplasm (Prdx5)
Anatomy Link Frequency
epithelium 3
Calu-3 1
Prdx5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 240 97.92 Very High Very High Very High
cytokine 18 43.84 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 228 97.92 Very High Very High Very High
Toxicity 12 96.84 Very High Very High Very High
Pneumonia 18 96.00 Very High Very High Very High
Stress 24 83.72 Quite High
Hypoxia 18 82.28 Quite High
Pulmonary Disease 6 61.48 Quite High
Asthma 6 58.56 Quite High
Hypersensitivity 12 57.56 Quite High
Acute Monocytic Leukemia 6 50.44 Quite High
Necrosis 6 24.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transcription of PRXV protein was not increased by exposure to bacteria in the A549 or Calu-3 cells.
Transcription (Transcription) of PRXV protein in Calu-3
1) Confidence 0.69 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1601951 Disease Relevance 0.46 Pain Relevance 0.20
One explanation is that the mechanisms regulating PRXV transcription cannot further increase expression in these cells, which are in constant direct contact with pathogens, antigens, and oxidants from the environment that are present in the bronchial tree in vivo.
Transcription (transcription) of PRXV
2) Confidence 0.60 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1601951 Disease Relevance 0.72 Pain Relevance 0.15
We then used a perfused tracheal segment in vivo rat model to determine whether short-term (4 hours) exposure to f-MLP (induced leukocyte migration) or bacterial (E. coli) LPS would enhance transcription and translation of PRXV in the tracheal epithelium.
Transcription (transcription) of PRXV in epithelium
3) Confidence 0.58 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1601951 Disease Relevance 0.46 Pain Relevance 0.23
Live P. aeruginosa bacteria up-regulates expression, but not transcription, of PRXV in cultured airway epithelium in the presence of serum
Transcription (transcription) of PRXV in epithelium
4) Confidence 0.45 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1601951 Disease Relevance 0.14 Pain Relevance 0.07
Exposure of isolated tracheal segment to CSE significantly reduced mRNA levels for PRXV and the amount of PRXV protein in the epithelium.
Transcription (levels) of PRXV in epithelium
5) Confidence 0.45 Published 2006 Journal J Inflamm (Lond) Section Body Doc Link PMC1601951 Disease Relevance 0.34 Pain Relevance 0.03
Studies in anesthetized rats and mice; PRXV expression determined by Western blot analyses and immunohistochemistry; PRXV m-RNA expression determined by Taq-Man RT-PCR.


Transcription (expression) of PRXV
6) Confidence 0.45 Published 2006 Journal J Inflamm (Lond) Section Abstract Doc Link PMC1601951 Disease Relevance 0.32 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox