INT198011

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Context Info
Confidence 0.20
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (BAX, MCL1) cytoplasm (BAX, MCL1) nucleus (BAX, MCL1)
cell differentiation (MCL1) nucleoplasm (MCL1) endoplasmic reticulum (BAX)
BAX (Homo sapiens)
MCL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 52 11.92 Low Low
cytokine 22 7.92 Low Low
COX-2 inhibitor 104 5.00 Very Low Very Low Very Low
cINOD 34 5.00 Very Low Very Low Very Low
antagonist 10 5.00 Very Low Very Low Very Low
aspirin 8 5.00 Very Low Very Low Very Low
Paracetamol 6 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 410 100.00 Very High Very High Very High
Carcinoma 102 96.44 Very High Very High Very High
Stress 10 53.84 Quite High
Death 61 50.00 Quite Low
Hepatocellular Cancer 15 50.00 Quite Low
Injury 3 49.52 Quite Low
Hepatitis 1 44.76 Quite Low
Cancer 273 37.12 Quite Low
Targeted Disruption 8 17.72 Low Low
INFLAMMATION 56 11.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
An important mode of action of Mcl-1 is the interaction with pro-apoptotic Bcl-2 family members (such as Bim [60], Bak, Bid and Bax).
Bax Binding (interaction) of Mcl-1 associated with apoptosis
1) Confidence 0.20 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1601962 Disease Relevance 0.83 Pain Relevance 0
Bax can form also a complex with the anti-apoptotic protein Bcl-xL [53] and Mcl-1 [14].
Bax Binding (complex) of Mcl-1 associated with apoptosis
2) Confidence 0.04 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 1.11 Pain Relevance 0
Bax can form also a complex with the anti-apoptotic protein Bcl-xL [53] and Mcl-1 [14].
Bax Binding (form) of Mcl-1 associated with apoptosis
3) Confidence 0.04 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 1.11 Pain Relevance 0

General Comments

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