INT198048

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Context Info
Confidence 0.28
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.05
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PDGFA) extracellular region (PDGFA) embryo development (PDGFA)
cell-cell signaling (PDGFA)
Anatomy Link Frequency
platelet 1
PDGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 20 83.12 Quite High
cytokine 76 80.80 Quite High
Inflammation 40 80.44 Quite High
fibrosis 1 67.72 Quite High
metalloproteinase 102 5.00 Very Low Very Low Very Low
COX-2 inhibitor 23 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 94 97.76 Very High Very High Very High
Infection 104 97.40 Very High Very High Very High
Herpes Simplex Virus 238 97.20 Very High Very High Very High
Apoptosis 116 91.52 High High
Cancer 41 83.12 Quite High
INFLAMMATION 44 80.44 Quite High
Hepatocellular Cancer 9 71.84 Quite High
Necrosis 2 69.28 Quite High
Malignant Neoplastic Disease 5 68.36 Quite High
Fibrosis 1 67.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrary, knockdown of Mcl-1 slightly sensitized HCC cells towards inhibition of mTOR by rapamycin (5 nM, 24 h, p < 0.01), selective inhibition of VEGF (Flk-1) and PDGF receptor tyrosine kinases by SU5614 (15 ?
Protein_catabolism (tyrosine) of PDGF associated with carcinoma
1) Confidence 0.28 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1601962 Disease Relevance 0.94 Pain Relevance 0
KSHV infection stimulated the secretion of growth factors and angiogenic factors such as insulin-like growth factor-1 (IGF-1), platelet derived growth factor-BB (PDGF-BB), macrophage colony stimulating factor (M-CSF), granulocyte colony-stimulating factor (G-CSF), GM-CSF, angiogenin (Ang), oncostatin-M (Onco-M), TPO (thrombopoietin), VEGF, stromal cell-derived factor-1 (SDF-1), SCF (stem cell factor), TGF-?
Protein_catabolism (growth) of PDGF in platelet associated with herpes simplex virus and infection
2) Confidence 0.17 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2820536 Disease Relevance 1.11 Pain Relevance 0.50

General Comments

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