INT198059

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Context Info
Confidence 0.34
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.46
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CACNA1I) transport (CACNA1I) transmembrane transport (CACNA1I)
Anatomy Link Frequency
occipital sulcus 1
white matter 1
CACNA1I (Homo sapiens)
Pain Link Frequency Relevance Heat
hyperexcitability 12 100.00 Very High Very High Very High
Migraine 106 99.32 Very High Very High Very High
headache 16 90.96 High High
depression 42 87.04 High High
Transcranial magnetic stimulation 4 78.96 Quite High
imagery 30 67.28 Quite High
Glutamate 2 29.20 Quite Low
Serotonin 6 5.00 Very Low Very Low Very Low
anticonvulsant 4 5.00 Very Low Very Low Very Low
beta blocker 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 102 99.32 Very High Very High Very High
Congenital Anomalies 26 97.72 Very High Very High Very High
Migraine With Aura 54 96.60 Very High Very High Very High
Migraine Without Aura 56 96.28 Very High Very High Very High
Migraine Disorders 12 91.68 High High
Epilepsy 38 87.68 High High
Depression 42 87.04 High High
Vomiting 10 79.92 Quite High
Cleidocranial Dysplasia 2 78.04 Quite High
Cadasil 2 9.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Area V3A is located in the transverse occipital sulcus and is specifically activated by coherent motion [20].
Positive_regulation (activated) of V3A in occipital sulcus
1) Confidence 0.34 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1609120 Disease Relevance 0.73 Pain Relevance 0.33
These findings, as well as the FA abnormalities in V3A supporting white matter, suggest the importance of this area in migraine during the interictal period, as hyperexcitability of the V3A area could contribute to the alteration of motion processing frequently observed in MWA and MWoA.
Positive_regulation (hyperexcitability) of V3A in white matter associated with migraine with aura, congenital anomalies, migraine, migraine without aura and hyperexcitability
2) Confidence 0.25 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1609120 Disease Relevance 1.73 Pain Relevance 0.82

General Comments

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