INT198062

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Context Info
Confidence 0.20
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.94
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CACNA1I) transport (CACNA1I) transmembrane transport (CACNA1I)
Anatomy Link Frequency
thickening 1
white matter 1
CACNA1I (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 106 99.68 Very High Very High Very High
depression 42 98.48 Very High Very High Very High
glial activation 2 89.52 High High
headache 16 87.12 High High
imagery 30 75.20 Quite High
hyperexcitability 12 58.12 Quite High
Serotonin 6 5.00 Very Low Very Low Very Low
anticonvulsant 4 5.00 Very Low Very Low Very Low
beta blocker 4 5.00 Very Low Very Low Very Low
Transcranial magnetic stimulation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 102 99.68 Very High Very High Very High
Depression 42 98.48 Very High Very High Very High
Migraine Without Aura 56 94.88 High High
Migraine With Aura 54 94.52 High High
Epilepsy 38 91.84 High High
Congenital Anomalies 26 77.20 Quite High
Migraine Disorders 12 63.44 Quite High
Cleidocranial Dysplasia 2 35.48 Quite Low
Nociception 2 28.40 Quite Low
Stroke 4 23.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alternatively, or in addition, the changes observed may also develop as the consequence of repetitive migraine attacks on the integrity of the cortical layers in V3A and MT+ and the subjacent white matter.
Regulation (integrity) of V3A in white matter associated with migraine
1) Confidence 0.20 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1609120 Disease Relevance 2.03 Pain Relevance 0.90
Similarity was found between the localization of cortical thickening in the mean thickness difference map of the 24 migraineurs compared with controls in V3A, and the location of the source of a CSD event in a single individual described in our previous work (Figure 2) [29].
Regulation (controls) of V3A in thickening associated with depression
2) Confidence 0.13 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1609120 Disease Relevance 0.91 Pain Relevance 0.13

General Comments

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