INT198074

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.65
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.25
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc1a1)
Anatomy Link Frequency
neuronal 2
nerve 2
Slc1a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 163 95.40 Very High Very High Very High
Hippocampus 26 87.92 High High
cerebral cortex 2 77.60 Quite High
long-term potentiation 2 75.48 Quite High
Neurotransmitter 8 50.00 Quite Low
chemokine 9 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
nMDA receptor 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 78 96.88 Very High Very High Very High
Anxiety Disorder 1 76.48 Quite High
Epilepsy 2 48.24 Quite Low
Generalized Anxiety Disorder 1 18.84 Low Low
Stress 24 5.00 Very Low Very Low Very Low
Disease 13 5.00 Very Low Very Low Very Low
Aging 12 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 12 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low
Shock 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In separate studies, we found that the levels of the SLC1A1 protein were increased in nerve ending particle (synaptosome) prepared from the brains of 12-mo-old Tg mice (1.39-fold) over those of wt mouse brain.
Positive_regulation (increased) of Gene_expression (levels) of SLC1A1 protein in nerve associated with targeted disruption
1) Confidence 0.65 Published 2010 Journal BMC Genomics Section Body Doc Link PMC2896956 Disease Relevance 0.17 Pain Relevance 0.50
Here we now show, in vivo, that after 24 h of altered sensory stimulation, their expression increases, whereas the expression levels of the neuronal transporter EAAC1 remain unchanged.
Positive_regulation (increases) of Gene_expression (expression) of neuronal transporter EAAC1 in neuronal
2) Confidence 0.37 Published 2006 Journal PLoS Biology Section Body Doc Link PMC1609127 Disease Relevance 0.08 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox