INT198075

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.02
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc1a1)
Slc1a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 80 90.88 High High
excitatory amino acid 3 74.64 Quite High
nMDA receptor 26 50.28 Quite High
Glutamate receptor 11 32.00 Quite Low
alcohol 1 19.52 Low Low
Neurotransmitter 16 12.16 Low Low
sSRI 68 5.00 Very Low Very Low Very Low
Serotonin 22 5.00 Very Low Very Low Very Low
Catechol-O-methyltransferase 14 5.00 Very Low Very Low Very Low
behavioral therapy 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 419 100.00 Very High Very High Very High
Obsessive-compulsive Disorder 24 5.00 Very Low Very Low Very Low
Cognitive Disorder 18 5.00 Very Low Very Low Very Low
Tourette's Syndrome 18 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 18 5.00 Very Low Very Low Very Low
Congenital Anomalies 14 5.00 Very Low Very Low Very Low
Chorea 10 5.00 Very Low Very Low Very Low
Streptococcal Infections 10 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Epilepsy 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, considerable consistency has been established in the reported associations between SLC1A1 and OCD.
SLC1A1 Binding (associations) of associated with anxiety disorder
1) Confidence 0.35 Published 2008 Journal Current Chemical Genomics Section Body Doc Link PMC2746669 Disease Relevance 0.53 Pain Relevance 0
A third independent investigation [89] also confirmed an association between OCD and SLC1A1 for both single marker and haplotype single nucleotide polymorphisms (SNPs) in the 3’ region of the gene, consistent with the earlier studies [83, 84].
SLC1A1 Binding (association) of associated with anxiety disorder
2) Confidence 0.35 Published 2008 Journal Current Chemical Genomics Section Body Doc Link PMC2746669 Disease Relevance 0.50 Pain Relevance 0.10
GLT1, GLAST, and EAAC1 levels were normalized to actin.


EAAC1 Binding (normalized) of
3) Confidence 0.34 Published 2006 Journal PLoS Biology Section Body Doc Link PMC1609127 Disease Relevance 0 Pain Relevance 0.05

General Comments

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