INT198122

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Context Info
Confidence 0.69
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Aqp9)
Anatomy Link Frequency
ductule 1
Aqp9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 8 5.00 Very Low Very Low Very Low
ketamine 6 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
hyperexcitability 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 6 92.32 High High
B-cell Lymphoma 4 72.68 Quite High
Death 4 67.92 Quite High
Injury 34 65.16 Quite High
Ganglion Cysts 18 59.88 Quite High
Disease 4 47.92 Quite Low
Targeted Disruption 12 14.08 Low Low
Body Weight 12 9.68 Low Low
Glaucoma 22 5.00 Very Low Very Low Very Low
Optic Nerve Injuries 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although little is known regarding the physiology of this androgen metabolite, in the present study it was capable of upregulating AQP9, indicating that 3?
Positive_regulation (upregulating) of AQP9
1) Confidence 0.69 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1615873 Disease Relevance 0 Pain Relevance 0
Whereas AQP9 mRNA increased at days 2 and 14, protein levels decreased at both time points.
Positive_regulation (increased) of AQP9
2) Confidence 0.43 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2831780 Disease Relevance 0.39 Pain Relevance 0
AQP9 mRNA decreased at day 7, while protein levels increased.
Positive_regulation (increased) of AQP9
3) Confidence 0.43 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2831780 Disease Relevance 0.46 Pain Relevance 0
Thus, it is unlikely that DHT resupplementation after castration was able to directly restore the AQP9 staining.
Positive_regulation (restore) of AQP9
4) Confidence 0.40 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1615873 Disease Relevance 0 Pain Relevance 0
Of particular note, testosterone alone was not capable of restoring AQP9 after castration or efferent ductule ligation [16,19].
Positive_regulation (restoring) of AQP9 in ductule
5) Confidence 0.40 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1615873 Disease Relevance 0 Pain Relevance 0

General Comments

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