INT19818

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Context Info
Confidence 0.32
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk, Ins1) extracellular space (Ins1) carbohydrate metabolic process (Ins1)
cytoplasm (Ins1)
Anatomy Link Frequency
pancreatic islets 2
Penk (Rattus norvegicus)
Ins1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 7 100.00 Very High Very High Very High
Endogenous opioid 1 96.56 Very High Very High Very High
Opioid 2 75.00 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results demonstrated that there is a dose-dependent stimulation of the insulin gene expression by enkephalins and that the increase in (pro)insulin biosynthesis in isolated pancreatic islets by endogenous opioid peptides occurs mainly on the pretranslational level.
enkephalin Positive_regulation (stimulation) of Gene_expression (expression) of insulin in pancreatic islets associated with endogenous opioid and enkephalin
1) Confidence 0.32 Published 1990 Journal Biomed. Biochim. Acta Section Abstract Doc Link 2097989 Disease Relevance 0 Pain Relevance 0.74

General Comments

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