INT198184

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.03
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (PLDN) cytosol (PLDN) endosome (PLDN)
plasma membrane (Antxr1) cytoplasm (PLDN)
PLDN (Homo sapiens)
Antxr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bacillus Anthracis Infection 51 98.36 Very High Very High Very High
Poisoning 57 94.48 High High
Death 30 42.96 Quite Low
Disease 9 40.80 Quite Low
Cancer 9 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 6 5.00 Very Low Very Low Very Low
Diphtheria 3 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To address the possible role of ANTXR2 in lethal toxin killing of Fischer 344 rats, we first confirmed that D683 mutant forms of PA can interact with rat ANTXR2 (rANTXR2) but not rat ANTXR1.
PA Neg (not) Binding (interact) of rANTXR2
1) Confidence 0.00 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1617126 Disease Relevance 0.33 Pain Relevance 0
To address the possible role of ANTXR2 in lethal toxin killing of Fischer 344 rats, we first confirmed that D683 mutant forms of PA can interact with rat ANTXR2 (rANTXR2) but not rat ANTXR1.
PA Neg (not) Binding (interact) of ANTXR1
2) Confidence 0.00 Published 2006 Journal PLoS Pathogens Section Body Doc Link PMC1617126 Disease Relevance 0.33 Pain Relevance 0
The receptor-bound metal ion and PA residue D683 are critical for ANTXR1-PA binding.
PA Binding (binding) of ANTXR1-PA
3) Confidence 0.00 Published 2006 Journal PLoS Pathogens Section Abstract Doc Link PMC1617126 Disease Relevance 0.38 Pain Relevance 0

General Comments

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