INT198538

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (HK1, Cox11) small molecule metabolic process (HK1) carbohydrate metabolic process (HK1)
transmembrane transport (HK1) cytosol (HK1) nucleolus (HK1)
HK1 (Homo sapiens)
Cox11 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 4 76.12 Quite High
ketamine 2 55.28 Quite High
Central nervous system 21 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 4 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low
Parkinson's Disease 3 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Hyperglycemia 2 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cox11 sequesters HKI by binding to HKI at a site that is distinct from the active site and effectively reduces the availability of [HKI]tot for catalysis.
HKI Binding (binding) of Cox11
1) Confidence 0.14 Published 2006 Journal PLoS Genetics Section Body Doc Link PMC1626108 Disease Relevance 0 Pain Relevance 0.24

General Comments

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