INT198598

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Context Info
Confidence 0.69
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.21
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CFH) extracellular region (CFH)
Anatomy Link Frequency
adipose tissue 1
CFH (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 8 96.28 Very High Very High Very High
tolerance 17 49.04 Quite Low
cytokine 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
drug abuse 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 64 99.60 Very High Very High Very High
Disorder Of Lipid Metabolism 9 98.64 Very High Very High Very High
Flavivirus Infection 80 98.20 Very High Very High Very High
INFLAMMATION 10 96.28 Very High Very High Very High
Infection 41 93.00 High High
Dengue 104 92.60 High High
Increased Venous Pressure Under Development 2 90.56 High High
Weight Loss 17 88.84 High High
Insulin Resistance 23 86.96 High High
Age-related Macular Degeneration 2 85.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This was expected, because the hybrid CFH/CFHL1 gene described here would not be picked up by genomic sequencing using CFH-specific primers

CFH cDNA Sequencing

Transcription (described) of CFH
1) Confidence 0.69 Published 2006 Journal PLoS Medicine Section Body Doc Link PMC1626556 Disease Relevance 0.14 Pain Relevance 0
For the first time, CFH gene expression was detected in human adipose tissue (significantly increased in subcutaneous compared with omental fat).
Transcription (detected) of CFH in adipose tissue associated with obesity
2) Confidence 0.51 Published 2010 Journal Diabetes Section Abstract Doc Link PMC2797922 Disease Relevance 1.28 Pain Relevance 0.05
Indeed, preliminary data from Acioli-Silva et al. [27] have suggested that individuals with a polymorphism that is associated with increased mRNA expression of factor H have a reduced susceptibility to developing DHF.
Transcription (expression) of factor H associated with flavivirus infection
3) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2728508 Disease Relevance 1.79 Pain Relevance 0

General Comments

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