INT198647

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.97
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF, HIF1A) cell differentiation (HIF1A) intracellular (TNF)
extracellular matrix organization (TNF) cytoplasm (HIF1A) signal transducer activity (HIF1A)
TNF (Homo sapiens)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 284 89.68 High High
cytokine 298 86.28 High High
Inflammatory mediators 2 60.72 Quite High
Inflammatory response 20 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 46 100.00 Very High Very High Very High
Disease 194 99.60 Very High Very High Very High
Hypoglycemia 12 98.08 Very High Very High Very High
Malaria 420 96.52 Very High Very High Very High
Sepsis 150 94.24 High High
Acid Base Imbalance 56 90.08 High High
INFLAMMATION 308 89.68 High High
Acidosis 32 77.28 Quite High
Stress 6 73.44 Quite High
Adhesions 24 21.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypoxia and TNF both induce HIF-1
TNF Positive_regulation (induce) of HIF-1 associated with hypoxia
1) Confidence 0.03 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 1.39 Pain Relevance 0.13
As with HIF-1, both hypoxia [273] and TNF [42] upregulate MIF.
TNF Positive_regulation (upregulate) of HIF-1 associated with hypoxia
2) Confidence 0.02 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 1.59 Pain Relevance 0.21

General Comments

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