INT198877

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Context Info
Confidence 0.32
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.62
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lrp1) endosome (Lrp1) plasma membrane (Lrp1)
nucleus (Lrp1) cytoplasm (Lrp1)
Lrp1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 2 99.64 Very High Very High Very High
fibrosis 2 87.64 High High
Inflammation 8 59.92 Quite High
long-term potentiation 12 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
nMDA receptor 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 2 87.64 High High
Coronary Heart Disease 1 77.88 Quite High
Targeted Disruption 9 76.28 Quite High
Alzheimer's Dementia 9 74.92 Quite High
Atherosclerosis 35 66.48 Quite High
Disease 34 66.28 Quite High
INFLAMMATION 9 59.92 Quite High
Neointima 2 56.96 Quite High
Carotid Stenosis 1 40.12 Quite Low
Pathologic Processes 1 39.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of a functional LRP minireceptor in vivo resulted in an increase of soluble A?
Regulation (functional) of Gene_expression (Overexpression) of LRP minireceptor
1) Confidence 0.32 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1635701 Disease Relevance 0.22 Pain Relevance 0
agonist exert beneficial effects on atheroslcerosis in LDL receptor related protein 1 (LRP1) deficient mice by inhibition of Smad, while TGF-?
Regulation (effects) of Gene_expression (atheroslcerosis) of LRP1 associated with agonist
2) Confidence 0.20 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2597201 Disease Relevance 0.40 Pain Relevance 0.17

General Comments

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