INT198899

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Context Info
Confidence 0.24
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.17
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Vldlr) extracellular space (Vldlr) nucleus (Vldlr)
lipid metabolic process (Vldlr)
Anatomy Link Frequency
cleavages 2
Vldlr (Mus musculus)
Pain Link Frequency Relevance Heat
long-term potentiation 36 99.56 Very High Very High Very High
antagonist 3 87.04 High High
nMDA receptor 15 82.56 Quite High
glial activation 3 79.80 Quite High
metalloproteinase 24 79.48 Quite High
cytokine 6 31.68 Quite Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 27 91.28 High High
Toxicity 6 36.72 Quite Low
Adhesions 18 28.48 Quite Low
Disease 99 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 27 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 15 5.00 Very Low Very Low Very Low
Amyloid Plaque 9 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Brain Injury 6 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, cleavages of ApoER2 and VLDLR are regulated in part by alternate splicing events.


Regulation (regulated) of Localization (cleavages) of VLDLR in cleavages
1) Confidence 0.24 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1635701 Disease Relevance 0 Pain Relevance 0.09
The release of soluble forms of ApoER2 and VLDLR is affected by the presence of splice variants.
Regulation (affected) of Localization (release) of VLDLR
2) Confidence 0.24 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1635701 Disease Relevance 0 Pain Relevance 0.10
Moreover, Reelin application enhanced LTP induction, which was dependent on the presence of both ApoER2 and VLDLR [97].
Regulation (dependent) of Localization (presence) of VLDLR associated with long-term potentiation
3) Confidence 0.24 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1635701 Disease Relevance 0.17 Pain Relevance 0.47

General Comments

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