INT198925

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Context Info
Confidence 0.14
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (App, Ldlr) endosome (Ldlr) transport (Ldlr)
Golgi apparatus (App) extracellular matrix organization (App) DNA binding (App)
App (Mus musculus)
Ldlr (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 8 27.60 Quite Low
long-term potentiation 12 5.00 Very Low Very Low Very Low
nMDA receptor 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 33 78.16 Quite High
Alzheimer's Dementia 9 70.72 Quite High
Targeted Disruption 9 42.04 Quite Low
Pathologic Processes 1 5.52 Low Low
Adhesions 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 5 5.00 Very Low Very Low Very Low
Amyloid Plaque 3 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Brain Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together these studies indicate that binding to APP is a common event for the LDLR family members and expression and proteolytic processing of these receptors can impact APP trafficking and processing.


APP Binding (binding) of LDLR
1) Confidence 0.14 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1635701 Disease Relevance 0.15 Pain Relevance 0

General Comments

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