INT198931

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dlg4, Lrp8) extracellular space (Lrp8) extracellular region (Lrp8)
structural molecule activity (Dlg4) protein complex assembly (Dlg4) cytoplasm (Dlg4)
Dlg4 (Mus musculus)
Lrp8 (Mus musculus)
Pain Link Frequency Relevance Heat
nMDA receptor 5 98.64 Very High Very High Very High
long-term potentiation 12 91.48 High High
antagonist 1 79.40 Quite High
glial activation 1 72.16 Quite High
metalloproteinase 8 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 9 94.48 High High
Toxicity 2 51.44 Quite High
Cognitive Disorder 1 16.56 Low Low
Disease 33 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 9 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 5 5.00 Very Low Very Low Very Low
Amyloid Plaque 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Brain Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This ApoER2 splice variant interacts with PSD-95, which is itself associated with NMDA receptor conductance [87,95].
PSD-95 Binding (interacts) of ApoER2 associated with nmda receptor
1) Confidence 0.06 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1635701 Disease Relevance 0.23 Pain Relevance 0.46

General Comments

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