INT198970

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Context Info
Confidence 0.47
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GAPDH) peptidase activity (ADAMTS3) extracellular region (ADAMTS3)
small molecule metabolic process (GAPDH) oxidoreductase activity (GAPDH) proteinaceous extracellular matrix (ADAMTS3)
GAPDH (Homo sapiens)
ADAMTS3 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 17 100.00 Very High Very High Very High
Osteoarthritis 40 50.00 Quite Low
Inflammation 5 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Mechanotransduction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 42 50.00 Quite Low
Disease 9 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Joint Instability 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Canine specific primers (Table 1) were developed for glyceraldehyde-3-phosphate dehydrogenase (GAPDH), collagen (COL) 1, COL 2, aggrecan, tissue inhibitor of matrix metalloproteinases (TIMP)-1, TIMP-2, matrix metalloproteinase (MMP)-1, MMP-3, MMP-13, Aggrecanase-1 (ADAMTS4), Aggrecanase-2 (ADAMTS5), inducible nitric oxide synthase (INOS), and cyclooxygenase-2 (COX-2) using canine sequences available in Genbank.
GAPDH Negative_regulation (inhibitor) of ADAMTS4 associated with metalloproteinase
1) Confidence 0.47 Published 2006 Journal J Orthop Surg Section Body Doc Link PMC1636033 Disease Relevance 0 Pain Relevance 0.35

General Comments

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