INT199098
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The specificity of SN50 has previously been confirmed in these same cultures by EMSA using an inactive peptide, SN50M.[37] These results suggest that Nox2 activation/induction is dependent on NF? | |||||||||||||||
| |||||||||||||||
|
To confirm that elevation of brain IL-6 and induction of Nox2 described above led to increased Nox2-dependent superoxide production in vivo, we assessed superoxide levels using confocal imaging of dihydroethidium (DHE) oxidation to its fluorescent product (ox-DHE) in fixed brain slices prepared from DHE-injected young mice, and from DHE-injected old mice that had been treated for 7 days prior to DHE with either no drug, or with the NADPH oxidase inhibitor, apocynin, in their drinking water. | |||||||||||||||
| |||||||||||||||
|
-stimulation also results in a relative increase in mRNA transcripts for both p47phox and gp91phox and an increase in p47phox protein expression in monocytes primed with INF? | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.