INT199100

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Context Info
Confidence 0.19
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Ncf1) cytosol (Ncf1) Golgi apparatus (Ncf1)
plasma membrane (Ncf1) cytoplasm (Ncf1)
Anatomy Link Frequency
monocytes 2
Ncf1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 6 66.24 Quite High
Inflammatory stimuli 2 10.96 Low Low
Inflammation 12 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 125 96.24 Very High Very High Very High
Obesity 169 95.84 Very High Very High Very High
Disease 59 88.00 High High
Stress 20 50.00 Quite Low
Congenital Anomalies 1 21.04 Low Low
INFLAMMATION 21 10.60 Low Low
Neutrophil Disorders 3 10.56 Low Low
Death 12 5.00 Very Low Very Low Very Low
Amyloid Plaque 7 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-stimulation also results in a relative increase in mRNA transcripts for both p47phox and gp91phox and an increase in p47phox protein expression in monocytes primed with INF?
Positive_regulation (increase) of Gene_expression (expression) of p47phox in monocytes
1) Confidence 0.19 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1637099 Disease Relevance 0.09 Pain Relevance 0.03
production and
                   upregulated expression of p47phox
                   NADPH oxidase without an additive effect of the two. 
Positive_regulation (upregulated) of Gene_expression (expression) of p47phox
2) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2852499 Disease Relevance 0.75 Pain Relevance 0

General Comments

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