INT199121

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Context Info
Confidence 0.13
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.44
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lipg) extracellular space (Lipg) extracellular region (Lipg)
lipid metabolic process (Lipg)
Anatomy Link Frequency
hepatocytes 2
muscles 2
Lipg (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 30 99.64 Very High Very High Very High
cytokine 9 87.12 High High
Inflammation 27 84.80 Quite High
fibrosis 13 64.88 Quite High
ischemia 1 39.16 Quite Low
Chronic pancreatitis 102 5.00 Very Low Very Low Very Low
Bile 15 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 167 99.96 Very High Very High Very High
Disorder Of Lipid Metabolism 14 93.84 High High
Targeted Disruption 50 91.44 High High
Death 3 86.52 High High
INFLAMMATION 28 84.80 Quite High
Fibrosis 1 64.88 Quite High
Fatigue 17 58.84 Quite High
Cv Unclassified Under Development 1 39.16 Quite Low
Obesity 14 37.28 Quite Low
Disease 30 34.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After induction of pancreatitis, levels of lipase (after 24 hours) and amylase (after 48 hours) were higher in R122H mice compared to controls.
Positive_regulation (higher) of Gene_expression (levels) of lipase associated with pancreatitis
1) Confidence 0.13 Published 2006 Journal BMC Gastroenterol Section Abstract Doc Link PMC1637108 Disease Relevance 0.98 Pain Relevance 0.08
agonist Wy14643 modestly induced hepatic lipase (Lipc) expression in primary human hepatocytes [24].
Positive_regulation (induced) of Gene_expression (expression) of lipase in hepatocytes associated with agonist
2) Confidence 0.10 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.47 Pain Relevance 0.10
Maximum tetanic force generation by EDL muscles was depressed by ?
Positive_regulation (generation) of Gene_expression (muscles) of EDL in muscles
3) Confidence 0.06 Published 2010 Journal American Journal of Physiology - Regulatory, Integrative and Comparative Physiology Section Body Doc Link PMC2806206 Disease Relevance 0.06 Pain Relevance 0
The animals showed slightly elevated serum levels of lipase without any significant histological alteration, suggesting a subtle acinar damage.
Positive_regulation (elevated) of Gene_expression (levels) of lipase
4) Confidence 0.03 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1774562 Disease Relevance 0.93 Pain Relevance 0.14

General Comments

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