INT199122

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.21
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.79
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 1
Thim (Mus musculus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 6 98.04 Very High Very High Very High
Inflammation 13 90.24 High High
opioid receptor 72 88.68 High High
Parenteral administration 3 83.56 Quite High
Hippocampus 27 72.40 Quite High
Opioid 21 68.72 Quite High
GABAergic 3 62.64 Quite High
Neurotransmitter 3 62.16 Quite High
Neuronal excitability 3 60.08 Quite High
Central grey 81 44.44 Quite Low
Disease Link Frequency Relevance Heat
Pancreatitis 44 98.04 Very High Very High Very High
Neurodegenerative Disease 6 94.24 High High
Disease 6 91.80 High High
INFLAMMATION 13 90.24 High High
Injury 3 79.92 Quite High
Apoptosis 8 74.84 Quite High
Decapitation 3 74.72 Quite High
Drug Induced Neurotoxicity 3 73.32 Quite High
Targeted Disruption 41 60.88 Quite High
Stress 3 54.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data argue for removal of THIM from all infant vaccines.



Negative_regulation (removal) of THIM
1) Confidence 0.21 Published 2010 Journal Neurochem Res Section Body Doc Link PMC2957583 Disease Relevance 0.15 Pain Relevance 0.14
Because in rats the second postnatal week is a period of dynamic developmental changes in hippocampal synaptogenesis [35], the loss of synaptophysin in THIM-exposed animals may suggest disruption of this process, excessive synaptic pruning, or neuronal degeneration.
Negative_regulation (loss) of THIM in neuronal
2) Confidence 0.15 Published 2010 Journal Neurochem Res Section Body Doc Link PMC2957583 Disease Relevance 0.30 Pain Relevance 0.47
A separate group of experimentally naïve rats, treated with two lower doses of THIM, 12 and 240 ?
Negative_regulation (doses) of THIM
3) Confidence 0.15 Published 2010 Journal Neurochem Res Section Body Doc Link PMC2957583 Disease Relevance 0.07 Pain Relevance 0
On the other hand, a loss of function mutation of anionic trypsinogen (PRSS2) protects against chronic pancreatitis [22].
Negative_regulation (loss) of mutation associated with chronic pancreatitis
4) Confidence 0.01 Published 2006 Journal BMC Gastroenterol Section Body Doc Link PMC1637108 Disease Relevance 1.27 Pain Relevance 0.38

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox