INT199129

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ctsb, PRSS1) extracellular space (Ctsb, PRSS1) extracellular region (Ctsb, PRSS1)
mitochondrion (Ctsb) lysosome (Ctsb) cytoplasm (Ctsb)
Ctsb (Mus musculus)
PRSS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 1 87.24 High High
Inflammation 7 83.36 Quite High
Chronic pancreatitis 6 67.12 Quite High
cytokine 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 44 91.36 High High
Necrosis 1 87.76 High High
Hemorrhage 1 87.24 High High
Edema 2 85.28 High High
INFLAMMATION 7 83.36 Quite High
Disease 6 81.60 Quite High
Targeted Disruption 41 50.00 Quite Low
Apoptosis 8 30.48 Quite Low
Body Weight 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As it is unclear in what cellular compartment this takes place, several pathways may be involved like trypsinogen autoactivation, trypsin activation by the lysosomal hydrolase cathepsin B, or reduced content or activity of the secretory trypsin inhibitor [2-4].
lysosomal hydrolase cathepsin B Positive_regulation (activation) of trypsin
1) Confidence 0.01 Published 2006 Journal BMC Gastroenterol Section Body Doc Link PMC1637108 Disease Relevance 0.90 Pain Relevance 0.15

General Comments

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