INT199189

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 0.30
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) signal transduction (Ros1)
mitochondrion (Aldh2) oxidoreductase activity (Aldh2) plasma membrane (Ros1)
Aldh2 (Mus musculus)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 172 97.36 Very High Very High Very High
Potency 28 5.00 Very Low Very Low Very Low
methotrexate 8 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Angina 4 5.00 Very Low Very Low Very Low
Bioavailability 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 60 75.00 Quite High
Cardiovascular Disease 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 4 5.00 Very Low Very Low Very Low
Reprotox - General 2 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to recent studies, mitochondrial ROS formation and oxidative inactivation of the organic nitrate bioactivating enzyme mitochondrial aldehyde dehydrogenase (ALDH-2) play an important role for the development of nitrate and cross-tolerance.


ALDH-2 Binding (formation) of mitochondrial ROS associated with tolerance
1) Confidence 0.06 Published 2006 Journal BMC Cardiovasc Disord Section Abstract Doc Link PMC1654181 Disease Relevance 0.07 Pain Relevance 0.22
According to recent studies, mitochondrial ROS formation and oxidative inactivation of the organic nitrate bioactivating enzyme mitochondrial aldehyde dehydrogenase (ALDH-2) play an important role for the development of nitrate and cross-tolerance.


ALDH-2 Binding (formation) of mitochondrial ROS associated with tolerance
2) Confidence 0.06 Published 2006 Journal BMC Cardiovasc Disord Section Abstract Doc Link PMC1654181 Disease Relevance 0.07 Pain Relevance 0.22
According to recent studies, mitochondrial ROS formation and oxidative inactivation of the organic nitrate bioactivating enzyme mitochondrial aldehyde dehydrogenase (ALDH-2) play an important role for the development of nitrate and cross-tolerance.


mitochondrial aldehyde dehydrogenase Binding (formation) of mitochondrial ROS associated with tolerance
3) Confidence 0.05 Published 2006 Journal BMC Cardiovasc Disord Section Abstract Doc Link PMC1654181 Disease Relevance 0.07 Pain Relevance 0.22
According to recent studies, mitochondrial ROS formation and oxidative inactivation of the organic nitrate bioactivating enzyme mitochondrial aldehyde dehydrogenase (ALDH-2) play an important role for the development of nitrate and cross-tolerance.


mitochondrial aldehyde dehydrogenase Binding (formation) of mitochondrial ROS associated with tolerance
4) Confidence 0.05 Published 2006 Journal BMC Cardiovasc Disord Section Abstract Doc Link PMC1654181 Disease Relevance 0.07 Pain Relevance 0.22

General Comments

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