INT199192

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.23
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Gnat3, Hmox1) signal transduction (Gnat3, Hmox1) endoplasmic reticulum (Hmox1)
enzyme binding (Hmox1) GTPase activity (Gnat3) cytoplasm (Gnat3)
Gnat3 (Mus musculus)
Hmox1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 86 89.20 High High
Bioavailability 2 49.04 Quite Low
Potency 14 42.84 Quite Low
Inflammation 2 24.92 Low Low
methotrexate 4 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 30 82.48 Quite High
INFLAMMATION 2 24.92 Low Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Reprotox - General 2 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is unclear why ISDN and GTN do not induce HO-1.
GTN Neg (not) Positive_regulation (induce) of HO-1
1) Confidence 0.27 Published 2006 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1654181 Disease Relevance 0.08 Pain Relevance 0.07
In contrast, GTN only induced a minor increase in HO-1 mRNA which did not reach significance (Figure 3).
GTN Positive_regulation (increase) of HO-1
2) Confidence 0.20 Published 2006 Journal BMC Cardiovasc Disord Section Body Doc Link PMC1654181 Disease Relevance 0.15 Pain Relevance 0.11

General Comments

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