INT199221
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Different studies have shown that factors which are associated with NASH in patients with NAFLD are male gender, age, the extent of obesity, type 2 diabetes, high levels of alanine aminotransferase, aspartate aminotransferase and triglycerides, high HOMA indices of insulin resistance, systemic hypertension, high levels of C-peptide [6,16-21], hyaluronic acid and type VI collagen [22], TNF-alpha and IL-8 [23], and serum acute phase proteins [24]. | |||||||||||||||
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The disappearance of the keratin immunostaining in ballooned hepatocytes is reasonably specific for ASH and NASH, since it is not seen in ballooned cells of viral hepatitis or toxic damage and can therefore be used as an objective morphologic parameter in grading of steatohepatitis (Lackner et al. 2008). | |||||||||||||||
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