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Context Info
Confidence 0.22
First Reported 1990
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.10
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ifng) extracellular region (Ifng)
Ifng (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 3 99.12 Very High Very High Very High
Morphine 4 97.42 Very High Very High Very High
cytokine 8 93.44 High High
Arthritis 1 92.88 High High
methotrexate 5 90.60 High High
dexamethasone 5 90.40 High High
corticosteroid 5 75.00 Quite High
Inflammation 1 71.84 Quite High
rheumatoid arthritis 1 69.44 Quite High
cINOD 1 69.24 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 100.00 Very High Very High Very High
Cancer 1 100.00 Very High Very High Very High
Arthritis 4 92.88 High High
Immunization 2 79.32 Quite High
Candida Infection 2 78.80 Quite High
INFLAMMATION 3 71.84 Quite High
Rheumatoid Arthritis 1 69.44 Quite High
Syndrome 1 33.20 Quite Low
Fever 1 30.72 Quite Low
Headache 1 30.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
D-PA failed to influence anti-OVA IgG, IgG2a and IgG1 production as well as IFN-gamma and IL-10 secretion.
Neg (failed) Regulation (influence) of Localization (secretion) of IFN-gamma
1) Confidence 0.22 Published 2005 Journal Int J Immunopathol Pharmacol Section Abstract Doc Link 15698518 Disease Relevance 0.59 Pain Relevance 0.58
In this model, the exposure to morphine (25 mg/kg, 5 days before, during and 5 days after inoculation with the yeast) significant decreased IL-2 and IL-4 levels, while secretion of IFN-gamma was unaltered.
Regulation (unaltered) of Localization (secretion) of IFN-gamma associated with morphine
2) Confidence 0.04 Published 2000 Journal Immunopharmacol Immunotoxicol Section Abstract Doc Link 10737255 Disease Relevance 0.31 Pain Relevance 0.59
A massive and self-limited release of tumor necrosis factor and interferon gamma was detected in the systemic circulation in 35 consecutive renal allograft recipients by specific radioimmunoassays very soon following the first injection of the monoclonal antibody OKT3 (anti-CD3).
Regulation (detected) of Localization (release) of interferon gamma associated with necrosis and cancer
3) Confidence 0.01 Published 1990 Journal Transplantation Section Abstract Doc Link 2109379 Disease Relevance 0.20 Pain Relevance 0.07

General Comments

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