INT199261

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mapt) cytoskeleton (Mapt) nucleus (Mapt)
enzyme binding (Mapt) cytoplasm (Mapt)
Mapt (Mus musculus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 2 92.20 High High
imagery 22 90.00 High High
opioid receptor 4 89.16 High High
mu opioid receptor 54 50.00 Quite Low
Central nervous system 24 5.00 Very Low Very Low Very Low
Spinal cord 20 5.00 Very Low Very Low Very Low
Substantia nigra 10 5.00 Very Low Very Low Very Low
Thalamus 6 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
Lasting pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 118 98.20 Very High Very High Very High
Neuroblastoma 2 28.56 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present studies, we establish a transgenic mouse model using a single transgenic construct that contains a 3.7 kb E11 promoter region and an 8.9 kb E1 promoter region to drive expression of two reporters, tau/LacZ and tau/GFP, respectively.
Negative_regulation (drive) of Gene_expression (expression) of tau/GFP associated with targeted disruption
1) Confidence 0.06 Published 2006 Journal BMC Mol Biol Section Body Doc Link PMC1657025 Disease Relevance 0.63 Pain Relevance 0.18
In the present studies, we establish a transgenic mouse model using a single transgenic construct that contains a 3.7 kb E11 promoter region and an 8.9 kb E1 promoter region to drive expression of two reporters, tau/LacZ and tau/GFP, respectively.
Negative_regulation (drive) of Gene_expression (expression) of tau/LacZ associated with targeted disruption
2) Confidence 0.06 Published 2006 Journal BMC Mol Biol Section Body Doc Link PMC1657025 Disease Relevance 0.62 Pain Relevance 0.18

General Comments

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