INT199269

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Context Info
Confidence 0.10
First Reported 2006
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 0
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Qsox1) oxidoreductase activity (Qsox1) extracellular region (Qsox1)
Golgi apparatus (Qsox1) endoplasmic reticulum (Qsox1)
Anatomy Link Frequency
proximal 2
Qsox1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 27 81.44 Quite High
agonist 1 68.84 Quite High
Morphine 2 27.44 Quite Low
Oxycodone 1 21.56 Low Low
methadone 1 21.00 Low Low
Codeine 1 20.56 Low Low
Analgesic 1 19.64 Low Low
Lasting pain 2 14.56 Low Low
Opioid 2 13.48 Low Low
Central nervous system 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 71 50.00 Quite Low
Cancer 4 48.00 Quite Low
Necrosis 1 47.52 Quite Low
Pain 2 14.56 Low Low
Repression 21 5.00 Very Low Very Low Very Low
Hyperplasia 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Exsanguination 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Breast Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
appaB, SOX, and neuron-restrictive silencer element (NRSE) in the proximal or distal promoters have been identified to interact with their trans-acting partners, which positively or negatively regulate the E1 promoter activity [29-42].
SOX Binding (interact) of in proximal
1) Confidence 0.10 Published 2006 Journal BMC Mol Biol Section Body Doc Link PMC1657025 Disease Relevance 0 Pain Relevance 0.20
To determine if cyclin D1 is a direct transcriptional target Sox17, the regulatory region of cyclin D1 was examined for putative Sox binding sites.
Sox Spec (examined) Binding (binding) of
2) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0
A well-conserved consensus Sox binding sequence was identified in cyclin D1 proximal promoter, located at approximately ?
Sox Binding (binding) of in proximal
3) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0
Sox proteins share homology in the HMG domain, which binds the consensus DNA sequence (A/T)(A/T)CAA(A/T)GG to regulate gene expression and mediates protein interactions with transcriptional cofactors [1].
Sox Binding (binds) of
4) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2682659 Disease Relevance 0 Pain Relevance 0

General Comments

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