INT199273

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Context Info
Confidence 0.11
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Tg(Foxn1)E1Hon (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 27 50.00 Quite Low
imagery 11 43.60 Quite Low
Potency 1 42.72 Quite Low
Kappa opioid receptor 1 9.84 Low Low
opioid receptor 2 6.80 Low Low
Central nervous system 12 5.00 Very Low Very Low Very Low
Spinal cord 10 5.00 Very Low Very Low Very Low
Substantia nigra 5 5.00 Very Low Very Low Very Low
Thalamus 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 78 94.40 High High
Targeted Disruption 66 92.24 High High
Cancer 58 74.76 Quite High
Recurrence 2 51.88 Quite High
Cirrhosis 4 49.04 Quite Low
Liver Cancer 2 40.76 Quite Low
Death 7 38.16 Quite Low
Apoptosis 37 34.28 Quite Low
Congenital Anomalies 1 13.92 Low Low
Infection 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We hope that by using the axon-targeting potential of tau/LacZ and tau/GFP reporters, we are able to map E11 and E1 promoter activities not only in their expressing cell bodies but also in their projections.
Negative_regulation (map) of E1
1) Confidence 0.11 Published 2006 Journal BMC Mol Biol Section Body Doc Link PMC1657025 Disease Relevance 0.24 Pain Relevance 0
This is a replication-defective adenovirus with deletion of E1 and E3 genes, which render this virus incapable of replication itself (18).
Negative_regulation (deletion) of E1
2) Confidence 0.03 Published 2008 Journal Carcinogenesis Section Body Doc Link PMC2516489 Disease Relevance 0.92 Pain Relevance 0

General Comments

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