INT199312

Context Info Confidence 0.01 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.76 Pain Relevance 0

extracellular space (Edn1, VEGFA) extracellular region (Edn1, VEGFA) cytoplasm (Edn1, VEGFA) growth (VEGFA) proteinaceous extracellular matrix (VEGFA) cell-cell signaling (Edn1)

Edn1 (Mus musculus) VEGFA (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 16 11.08 cINOD 7 5.00 cytokine 3 5.00 endometriosis 2 5.00 Inflammatory stimuli 2 5.00 aspirin 1 5.00 Inflammatory response 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Ovarian Cancer 42 99.08 Cancer 60 77.92 Malignant Neoplastic Disease 44 73.00 Cyst 11 59.32 Injury 1 34.24 Rupture 1 29.40 Benign Tumor 3 21.92 INFLAMMATION 19 11.08 Increased Venous Pressure Under Development 1 6.28 Adenocarcinoma 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Since ET-1 is known regulator of VEGF, this effect might be mediated by COX-1/PGE2 in these cells.

ET-1 Negative_regulation (regulator) of VEGF

1) Confidence 0.01 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1657027 Disease Relevance 0.76 Pain Relevance 0

General Comments

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