INT199359

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 2006
Last Reported 2006
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Macf1) carbohydrate metabolic process (Igf2) cytoplasm (Macf1)
extracellular space (Igf2) extracellular region (Igf2) cytoskeleton (Macf1)
Anatomy Link Frequency
colon 1
Igf2 (Mus musculus)
Macf1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aberrant Crypt Foci 84 100.00 Very High Very High Very High
Targeted Disruption 160 98.42 Very High Very High Very High
Cancer 190 92.64 High High
Colon Cancer 82 71.84 Quite High
Colorectal Cancer 12 44.24 Quite Low
Familial Adenomatous Polyposis 4 37.96 Quite Low
Adenoma 72 5.00 Very Low Very Low Very Low
Apoptosis 30 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low
Carcinoma 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DMH treatment did not induce the expression of IGF2 in the colon of mice, indicating that the effect of IGF-II on preneoplastic alterations (ACF) in the colon was due to the IGF-II transgene.


IGF-II Regulation (effect) of ACF in colon associated with aberrant crypt foci
1) Confidence 0.11 Published 2006 Journal J Carcinog Section Body Doc Link PMC1660565 Disease Relevance 1.57 Pain Relevance 0
Since serum IGF-II levels in transgenic animals were still higher at this time point when compared to wild-type mice, IGF-II seems not to affect numbers of ACF at a later stage (Fig. 2B).
IGF-II Neg (not) Spec (seems) Regulation (affect) of ACF associated with aberrant crypt foci and targeted disruption
2) Confidence 0.10 Published 2006 Journal J Carcinog Section Body Doc Link PMC1660565 Disease Relevance 1.54 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox