INT199395

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.86
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Mip, Trpv1) plasma membrane (Mip, Trpv1) transmembrane transport (Mip, Trpv1)
cytosol (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
neurons 2
Mip (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 31 98.96 Very High Very High Very High
Pain 12 97.44 Very High Very High Very High
dorsal root ganglion 26 95.86 Very High Very High Very High
Hyperalgesia 5 83.80 Quite High
Inflammation 13 75.84 Quite High
cytokine 1 67.68 Quite High
Potency 1 51.60 Quite High
IPN 6 43.52 Quite Low
withdrawal 8 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 12 97.44 Very High Very High Very High
Ganglion Cysts 26 95.86 Very High Very High Very High
Hyperalgesia 6 83.80 Quite High
Nociception 31 80.96 Quite High
INFLAMMATION 19 75.84 Quite High
Inflammatory Pain 6 43.52 Quite Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 2 5.00 Very Low Very Low Very Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although both PKR1 and PKR2 are expressed in the DRG neurons, a recent report that mice lacking the PKR1 gene exhibit impaired pain perception to various stimuli including noxious heat, mechanical, capsaicin, and protons implies that PKR1 is likely to be the dominant receptor that exerts a tonic activation of TRPV1 [13].
dominant receptor Positive_regulation (exerts) of Positive_regulation (activation) of TRPV1 in neurons associated with pain, dorsal root ganglion and qutenza
1) Confidence 0.01 Published 2006 Journal Mol Pain Section Body Doc Link PMC1660571 Disease Relevance 0.86 Pain Relevance 0.69

General Comments

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