INT199396

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Context Info
Confidence 0.43
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) cell proliferation (Prok2) transport (Trpv1)
extracellular region (Prok2) plasma membrane (Trpv1) transmembrane transport (Trpv1)
Anatomy Link Frequency
neurons 1
Prok2 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 26 99.34 Very High Very High Very High
bradykinin 1 88.64 High High
Inflammation 13 87.20 High High
qutenza 31 80.36 Quite High
Pain 12 70.80 Quite High
Inflammatory response 8 54.00 Quite High
substance P 1 29.36 Quite Low
IPN 6 16.52 Low Low
Thermal hyperalgesia 1 15.76 Low Low
withdrawal 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 26 99.34 Very High Very High Very High
Nociception 31 92.28 High High
INFLAMMATION 19 87.20 High High
Injury 2 86.56 High High
Hypersensitivity 1 77.52 Quite High
Pain 12 70.80 Quite High
Pressure And Volume Under Development 2 47.88 Quite Low
Neurogenic Inflammation 2 28.08 Quite Low
Inflammatory Pain 6 16.52 Low Low
Hyperalgesia 6 15.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since PKR1 and PKR2, two G-protein coupled receptors, co-express with TRPV1 in the DRG neurons, it is very likely that PK2 would also sensitize TRPV1 by activating PKRs.
PK2 Regulation (sensitize) of TRPV1 in neurons associated with dorsal root ganglion
1) Confidence 0.43 Published 2006 Journal Mol Pain Section Body Doc Link PMC1660571 Disease Relevance 1.23 Pain Relevance 0.94

General Comments

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