INT199488

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) extracellular space (Il4) extracellular region (Il4)
plasma membrane (Oprm1) signal transducer activity (Oprm1)
Anatomy Link Frequency
immune cells 2
Il4 (Rattus norvegicus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 18 99.08 Very High Very High Very High
Analgesic 16 98.20 Very High Very High Very High
midbrain 2 95.56 Very High Very High Very High
cytokine 7 86.88 High High
Inflammation 65 76.04 Quite High
Nerve growth factor 5 71.60 Quite High
opioid receptor 94 69.88 Quite High
Spinal cord 11 64.84 Quite High
Pain 38 50.40 Quite High
analgesia 56 50.00 Quite Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 92.84 High High
Cancer 3 86.16 High High
Necrosis 2 85.68 High High
Neuroblastoma 1 80.88 Quite High
INFLAMMATION 70 76.04 Quite High
Pain 37 50.40 Quite High
Ganglion Cysts 12 49.60 Quite Low
Nociception 9 45.12 Quite Low
Neuropathic Pain 5 29.28 Quite Low
Osteoarthritis 1 23.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interleukin-4 stimulates MOR transcription in cultured immune cells and cultured neurons via transcription 6 (STAT6) activation of the MOR gene promoter (Kraus et al 2001).
Interleukin-4 Positive_regulation (stimulates) of Transcription (transcription) of MOR in immune cells
1) Confidence 0.01 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661636 Disease Relevance 0.84 Pain Relevance 0.73

General Comments

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