INT199493

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ngf) extracellular space (Ngf) extracellular region (Ngf)
plasma membrane (Oprd1) cytoplasm (Oprd1) signal transducer activity (Oprd1)
Ngf (Mus musculus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 94 100.00 Very High Very High Very High
Nerve growth factor 5 100.00 Very High Very High Very High
intrathecal 2 98.44 Very High Very High Very High
Opioid 127 97.44 Very High Very High Very High
Neuropathic pain 3 95.88 Very High Very High Very High
dorsal root ganglion 11 95.28 Very High Very High Very High
Inflammation 65 87.88 High High
cytokine 7 84.80 Quite High
Morphine 18 67.36 Quite High
Analgesic 16 66.48 Quite High
Disease Link Frequency Relevance Heat
Nociception 9 97.84 Very High Very High Very High
Neuropathic Pain 5 95.88 Very High Very High Very High
Ganglion Cysts 12 95.28 Very High Very High Very High
Targeted Disruption 3 90.92 High High
INFLAMMATION 70 87.88 High High
Necrosis 2 77.44 Quite High
Cancer 3 77.08 Quite High
Pain 37 50.00 Quite Low
Neuroblastoma 1 49.16 Quite Low
Stress 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further evidence that NGF influences opioid receptor function is provided by findings that intrathecal NGF restored opioid effectiveness in a rat model of neuropathic pain (Cahill, Dray, et al 2003).
NGF Regulation (influences) of opioid receptor associated with nerve growth factor, neuropathic pain, opioid receptor, opioid and intrathecal
1) Confidence 0.05 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661636 Disease Relevance 1.05 Pain Relevance 1.15

General Comments

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