INT199494

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crh) extracellular region (Crh) plasma membrane (Pdyn)
response to stress (Crh) cytoplasm (Crh)
Crh (Rattus norvegicus)
Pdyn (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 17 100.00 Very High Very High Very High
noradrenaline 10 100.00 Very High Very High Very High
Opioid 127 94.48 High High
cytokine 7 86.84 High High
Inflammatory response 1 85.60 High High
Inflammation 65 82.56 Quite High
antagonist 11 82.56 Quite High
analgesia 56 75.32 Quite High
Endogenous opioid 37 73.32 Quite High
antinociception 37 67.96 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 70 85.60 High High
Stress 18 74.64 Quite High
Pain 37 50.00 Quite Low
Nociception 9 46.68 Quite Low
Adhesions 13 5.00 Very Low Very Low Very Low
Ganglion Cysts 12 5.00 Very Low Very Low Very Low
Inflammatory Pain 6 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CRF induces the release of END, ENK, and DYN (Cabot et al 2001); noradrenaline releases END (Binder et al 2004; Mousa et al 2004); and IL-1?
CRF Positive_regulation (induces) of Localization (releases) of DYN associated with noradrenaline and enkephalin
1) Confidence 0.02 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661636 Disease Relevance 0.43 Pain Relevance 1.40

General Comments

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