INT19950

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Context Info
Confidence 0.16
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 14
Disease Relevance 4.72
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Abo) transferase activity, transferring glycosyl groups (Abo) Golgi apparatus (Abo)
carbohydrate metabolic process (Abo)
Anatomy Link Frequency
hepatocytes 1
saliva 1
Abo (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 347 92.28 High High
agonist 60 75.52 Quite High
Bile 18 71.52 Quite High
Nicotine 2 62.16 Quite High
Hippocampus 8 58.56 Quite High
Glutamate 2 34.52 Quite Low
Paracetamol 1 26.24 Quite Low
Opioid 57 18.32 Low Low
Inflammation 54 5.00 Very Low Very Low Very Low
Physical dependence 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 284 98.48 Very High Very High Very High
Aging 20 97.04 Very High Very High Very High
Disease 87 91.44 High High
Gastroenteritis 33 87.24 High High
Apoptosis 57 86.20 High High
Infection 49 85.40 High High
Deafness 18 81.32 Quite High
Atherosclerosis 9 77.68 Quite High
Toxicity 2 67.88 Quite High
Hypertension 2 66.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The membrane-bound transferase expressed in yeast in glycosylated as indicated by its enhanced electrophoretic mobility in a SDS-polyacrylamide gel following endoglycosidase H treatment and detection by Western immunoblot analysis.
Gene_expression (expressed) of transferase
1) Confidence 0.16 Published 1990 Journal Biochemistry Section Abstract Doc Link 2110831 Disease Relevance 0.09 Pain Relevance 0.05
Consistent with the presence of mRNA, pUDPGTm-1c-transformed AH22 cells synthesize a transferase protein with Mr congruent to 51,000 by Western immunoblot analysis.
Gene_expression (synthesize) of transferase
2) Confidence 0.16 Published 1990 Journal Biochemistry Section Abstract Doc Link 2110831 Disease Relevance 0.09 Pain Relevance 0
Proteins with transferase activity, including methionine adenosyltransferase II, ?
Gene_expression (activity) of transferase
3) Confidence 0.12 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.29 Pain Relevance 0.27
The truncated cDNA (lacking the putative membrane-insertion signal-peptide coding sequence, but with a newly adapted translation-start codon) is ligated into pAAH5 and is expressed as a cytosolic transferase form in the protease-deficient ZA521 strain of S. cerevisiae.
Gene_expression (expressed) of transferase associated with sprains and strains
4) Confidence 0.12 Published 1990 Journal Biochemistry Section Abstract Doc Link 2110831 Disease Relevance 0.15 Pain Relevance 0.09
In addition they measured the synthesis of AdoMet by adenosyl transferase and AdoMet utilization by COMT, and concluded that the decrease in AdoMet levels was a consequence of increased utilization during aging.
Gene_expression (utilization) of transferase associated with aging
5) Confidence 0.10 Published 2009 Journal Neurol Sci Section Body Doc Link PMC2746292 Disease Relevance 0.63 Pain Relevance 0.03
Expression of hypoxanthine guanine phosphoribosyl transferase 1 (Hprt1) transcript with a stable level between the strains and after the treatment was quantified to control for variation in cDNA amounts.
Gene_expression (Expression) of transferase associated with sprains and strains
6) Confidence 0.09 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.10 Pain Relevance 0.06
T) and thus are incomplete nonsecretors, producing small amounts of ABO and Leb HBGA in secretions.
Gene_expression (amounts) of ABO
7) Confidence 0.08 Published 2010 Journal Emerging Infectious Diseases Section Body Doc Link PMC2874438 Disease Relevance 1.07 Pain Relevance 0
None of the nonsecretors who were also Lewis negative (n = 3), hence lacking the Lea antigen and ABO in saliva, were symptomatically infected.
Gene_expression (antigen) of ABO in saliva
8) Confidence 0.08 Published 2010 Journal Emerging Infectious Diseases Section Body Doc Link PMC2874438 Disease Relevance 0.49 Pain Relevance 0
Moreover, no statistical difference in susceptibility was found between persons of different Lewis or ABO phenotypes.
Gene_expression (phenotypes) of ABO
9) Confidence 0.07 Published 2010 Journal Emerging Infectious Diseases Section Abstract Doc Link PMC2874438 Disease Relevance 0.68 Pain Relevance 0
Using immunohistochemical techniques they showed that qualitative levels of super-oxide dismutase, glutamyl transferase and 4-hydroxynonenal increase between 3 month old and 9 month old B6 mice; and differ from the levels detected in age-matched, normal hearing CBA/CaJ mice.
Gene_expression (levels) of glutamyl transferase
10) Confidence 0.02 Published 2010 Journal J Occup Med Toxicol Section Body Doc Link PMC2868036 Disease Relevance 0.80 Pain Relevance 0
The A. paniculata ethanol extract, EtOAc extract and andrographolide induce the expression of the pi class of glutathione S-transferase, a phase II biotransformation enzymes involved in detoxification of various classes of environmental carcinogens, in rat primary hepatocytes [99].
Gene_expression (expression) of transferase in hepatocytes
11) Confidence 0.01 Published 2010 Journal Chin Med Section Body Doc Link PMC2881933 Disease Relevance 0.33 Pain Relevance 0.06
governs metabolism of amino acids by suppressing expression of genes involved in transamination (Aspartate amino transferase (Got1), Alanine amino transferase (Gpt), Alanine glyoxylate aminotransferase (Agtx2), and deamination (Glutaminase (Gls)), as well as numerous genes that are part of the urea cycle (Cps1, Otc, Ass1, and Asl) [160, 161, 245].
Gene_expression (expression) of Alanine amino transferase
12) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0 Pain Relevance 0.14
governs metabolism of amino acids by suppressing expression of genes involved in transamination (Aspartate amino transferase (Got1), Alanine amino transferase (Gpt), Alanine glyoxylate aminotransferase (Agtx2), and deamination (Glutaminase (Gls)), as well as numerous genes that are part of the urea cycle (Cps1, Otc, Ass1, and Asl) [160, 161, 245].
Gene_expression (expression) of Aspartate amino transferase
13) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0 Pain Relevance 0.14
Alternatively, it has been recently demonstrated that both yeast and human TERT can function as a template- and RNA-independent terminal transferase (TT) for DNA synthesis in the presence of Mn2+ [90].
Gene_expression (synthesis) of transferase
14) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2561060 Disease Relevance 0 Pain Relevance 0

General Comments

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