INT199503

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Oprk1) cytoplasm (ENG) signal transduction (Oprk1)
extracellular space (ENG) nucleolus (ENG) cell adhesion (ENG)
ENG (Homo sapiens)
Oprk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 17 100.00 Very High Very High Very High
analgesia 56 99.68 Very High Very High Very High
Inflammation 65 98.68 Very High Very High Very High
antagonist 11 97.72 Very High Very High Very High
opioid receptor 94 97.48 Very High Very High Very High
Endogenous opioid 37 96.70 Very High Very High Very High
antinociception 37 92.72 High High
narcan 5 72.68 Quite High
noradrenaline 10 72.40 Quite High
Antinociceptive 7 60.52 Quite High
Disease Link Frequency Relevance Heat
Stress 18 99.34 Very High Very High Very High
INFLAMMATION 70 98.68 Very High Very High Very High
Nociception 9 85.00 Quite High
Pain 37 52.08 Quite High
Inflammatory Pain 6 43.12 Quite Low
Adhesions 13 5.00 Very Low Very Low Very Low
Ganglion Cysts 12 5.00 Very Low Very Low Very Low
Infection 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The use of antibodies against specific endogenous opioid peptides and selective opioid receptor antagonists reveal that at the early stages of inflammation, the peripheral component of CWS-evoked analgesia is mediated by END, ENK, and DYN, which activate MOR, DOR, and KOR (Machelska et al 2003).
END Positive_regulation (activate) of KOR associated with stress, inflammation, antagonist, endogenous opioid, enkephalin, opioid receptor and analgesia
1) Confidence 0.01 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661636 Disease Relevance 0.87 Pain Relevance 1.69

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox